Dr. Larissa O'Neill, MD
Medical Director · Founder
Leads hormone optimization, GLP-1 weight loss, peptide therapy, and longevity. Every wellness protocol is authored under her direction.
A physician-led practice in Georgetown, Texas — integrating injectables, lasers, and skin therapy with hormone optimization, GLP-1 weight loss, peptide pharmacology, and regenerative medicine. One chart. One trajectory.
Georgetown's only practice built around all four layers of medical optimization — working in sequence, on one chart. We measure before we treat, and treat before we refine.
Every plan starts with objective baselines. InBody maps muscle and fat, VO₂ max testing reads your metabolism, resting rate and training zones, Aura 3D sees sun damage beneath the surface, and genetic panels show how you're wired — data first, never guesswork. Learn about our diagnostics →
We restore what time and physiology have shifted. Compounded GLP-1 recalibrates appetite, peptide therapy supports recovery and sleep, hormone optimization rebuilds energy and drive, and IV & nutrient therapy tops you up — all managed by licensed providers.
For patients exploring cellular repair: exosome & stem-cell consults, topical exosomes for post-procedure recovery, PRF & PDGF drawn from your own platelets, and medical hair restoration — investigational, disclosed in full, never overclaimed.
Once the chemistry is right, the aesthetic work lasts. Neurotoxins & dermal filler soften lines and restore structure, laser & energy refine tone and texture, and microneedling, peels & threads bring back skin that catches light — timed to your wellness calendar.
Aesthetic and wellness services are integrated by design — your hormone status informs your skin's response, and your skin's response informs the cadence of care. Browse the practice below.
Tell us what you'd like to address — we'll surface the protocols (aesthetic, longevity, or both) most often paired with that goal. Every recommendation is a conversation, not a prescription.
Every patient — aesthetic or longevity — moves through the same clinical workflow. Diagnostics first. Prescription after.
A sit-down clinical interview — history, symptoms, prior interventions, and goals. No menu, no upsell.
Comprehensive lab panel: sex hormones, pituitary, thyroid, metabolic, lipid, CBC — drawn the same day where indicated.
Your clinician authors a written, versioned plan from your results — and we walk through it together at signing.
Re-evaluation at 6 — 8 weeks, then quarterly to bi-annually. Doses titrate to symptoms and labs together.
The most under-discussed reason a filler holds, a peel responds, or a microneedling result lasts: endocrine status. Estradiol regulates collagen density. Testosterone influences muscle protein synthesis and dermal thickness. We address the chemistry under the skin first — then the skin itself.
Bioidentical hormone replacement at Bespoke is delivered through EvexiPEL® subcutaneous pellets, compounded transdermal preparations, or injections — selected by your lab response and your lifestyle. Quarterly monitoring built in.
You will see the same faces every visit — and the same faces will read your labs, place your pellet, perform your injection, and track your skin over time. Continuity is structural.
Leads hormone optimization, GLP-1 weight loss, peptide therapy, and longevity. Every wellness protocol is authored under her direction.
Full-scope clinician — leads the injectable and aesthetic program and co-manages hormones, GLP-1, and peptides. The thread that runs through every service line.
Manages hormone optimization follow-ups and GLP-1 check-ins — keeping protocols tuned between visits and labs on schedule.
Runs the entire laser and energy-device program — Clarity II, Hollywood Spectra, LaseMD, Genius RF — plus medical-grade peels and facials.
Banked aesthetic credit, a sequenced year of laser, and a physician-led medical weight-loss program — three ways to make the work consistent, managed by your clinician on one chart. Explore all memberships →
Verified Google & in-office reviews from the last twelve months.
By far the best in Georgetown. The kindness and the professionalism speak for themselves — and Dr. O'Neill's expertise in women's health is unmatched.
First clinic that took the time to actually run my labs before recommending a plan. Sleep is better, energy is back, and the skin work is finally holding.
Krista is a precise injector who never overdoes it. I look like myself, just rested. That's exactly what I wanted.
One chart. One trajectory. One team that knows your name.
Your first appointment is a structured clinical interview and blood draw. Protocol design follows results — never the other way around. Most patients leave with a written plan and a follow-up in hand.
Plus: how we’d use a summer with the schedule on your side. One page, refreshed each month.
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