Semaglutide vs. tirzepatide: which path?
Both semaglutide and tirzepatide have transformed medical weight loss. They're related but not identical, and the right choice depends on you — your goals, your history, your labs, and how your body responds.
How they work
Semaglutide is a GLP-1 receptor agonist: it mimics a gut hormone that curbs appetite, slows stomach emptying, and improves how your body handles insulin. Tirzepatide is a dual agonist — it acts on both GLP-1 and GIP receptors, a second pathway that can mean stronger appetite control for some patients.
What the difference means for you
- Appetite & satiety — many patients report tirzepatide feels "stronger," but plenty do beautifully on semaglutide.
- Tolerability — side effects (nausea, GI changes) vary by person and are managed with careful titration.
- Cost — tirzepatide typically carries a higher monthly fee.
How we decide together
This isn't a coin flip. At your consult we review your history and baseline labs, then your provider recommends a medication and starting dose. Everything is medically supervised and in-person — not a mail-order subscription. Your medical management — provider visits, labs, MIC injections and body-composition scans — is bundled into one monthly fee; your medication is billed separately by the dispensing pharmacy.
Protecting muscle while you lose fat
Rapid weight loss can cost you muscle if it isn't watched. We track fat versus lean mass with InBody scans, and pair your program with peptides or hormone optimization when it makes sense — so what you lose is fat, not strength.
The medication is the tool. The supervision, labs, and body-composition tracking are what make it work safely.
See the full program on the Weight Loss membership page, or book a consultation to find your fit.
Compounded semaglutide and tirzepatide are prescribed at a provider's discretion after evaluation. Compounded medications are not FDA-approved products. Individual results vary.
